Current Research

Chronic neuropathic pain severely affects the quality of life of the individual patient and represents a major health issue for society with considerable economic consequences, e.g. increased medical expenses and public pension expenditure.

Chronic pain is difficult to treat and can seldom be cured, but in many cases it can be reduced, and a means to improve the treatment is to increase our knowledge of the underlying mechanisms. 

The Danish Pain Research Center was founded with the primary aim to study chronic pain, in particular neuropathic pain, defined by IASP as: Pain caused by a lesion or disease affecting the somatosensory system (Jensen et al., Pain 2011).

The current focus areas are:

  • Understanding risk factors and determinants for neuropathic pain
     

  • Understanding the development of painful and non-painful neuropathy as a consequence of diabetes and chemotherapy

  • Neuropathic pain following surgery and injury including postamputation pain
     

  • Pain following CNS lesions (stroke and spinal cord injury)
     

  • The sympathetic nervous system and pain
     

  • Pain physiology, including understanding cold sensory processing
     

  • Pharmacotherapy
     

 

 
   Ongoing projects
 

 

Understanding risk factors and determinants for neuropathic pain - DOLORisk EU project (2015-2019)
http://dolorisk.eu
 
IDNC - The International Diabetic Neuropathy Consortium (2015-2021) www.idnc.au.dk
 
Kristine Jepsen Bennedsgaard
PhD project: Mechanisms of oxaliplatin-induced neuropathy
 
Alexander Gramm Kristensen PhD project: Understanding underlying mechanisms of diabetic polyneuropathy
 
Sandra Sif Gylfadottir
PhD project: Painful diabetic neuropathy
 
Karolina Snopek
PhD project: Resistance training in patients with diabetic polyneuropathy
 
Francesca Fardo
Postdoc project: High precision magneto-encephalography of pain and temperature-related brain signals
 
Páll Karlsson
Postdoc project: Sensory changes, orofacial somatosensory function and nerve fiber analysis on diabetic neuropathy patients and healthy controls